To use a new variant of the CRISPR gene editing tool and the Cas13d protein to destroy the SARS-CoV-2 coronavirus genome.

The non-toxicity and efficiency of CRISPR reagents and Cas13d protein will be validated in vivo in zebrafish embryos. The efficiency of the project will be explored with the help of two related viruses (equine torovirus BEV, human coronavirus 229E) that allow working under BSL2 security conditions, before adapting the project to focus directly on the SARS-CoV-2 coronavirus genome under BSL3 conditions.   

Principal Investigator: Dolores Rodríguez (CNB)        

We use cookies on this site to improve your user experience. More info. ACEPTAR

Aviso de cookies